Dexamethasone and 1,25-Dihydroxyvitamin D3 Reduce Oxidative Stress-Related DNA Damage in Differentiating Osteoblasts

The process of osteoblast differentiation is regulated by several factors, including RUNX2. Recent reports suggest an involvement of RUNX2 in DNA damage response (DDR), which is important due to association of differentiation with oxidative stress. In the present work we explore the influence of two...

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Bibliographic Details
Main Authors: Pawlowska, Elzbieta, Wysokiński, Daniel, Tokarz, Paulina, Piastowska-Ciesielska, Agnieszka, Szczepanska, Joanna, Blasiak, Janusz
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200756/