Endogenous Retrovirus Insertion in the KIT Oncogene Determines White and White spotting in Domestic Cats

The Dominant White locus (W) in the domestic cat demonstrates pleiotropic effects exhibiting complete penetrance for absence of coat pigmentation and incomplete penetrance for deafness and iris hypopigmentation. We performed linkage analysis using a pedigree segregating White to identify KIT (Chr. B...

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Bibliographic Details
Main Authors: David, Victor A., Menotti-Raymond, Marilyn, Wallace, Andrea Coots, Roelke, Melody, Kehler, James, Leighty, Robert, Eizirik, Eduardo, Hannah, Steven S., Nelson, George, Schäffer, Alejandro A., Connelly, Catherine J., O’Brien, Stephen J., Ryugo, David K.
Format: Online
Language:English
Published: Genetics Society of America 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199695/