Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci

Male fertility requires the continuous production of high quality motile spermatozoa in abundance. Alterations in all three metrics cause oligoasthenoteratozoospermia, the leading cause of human sub/infertility. Post-mitotic spermatogenesis inclusive of several meiotic stages and spermiogenesis (ter...

Full description

Bibliographic Details
Main Authors: Comazzetto, Stefano, Di Giacomo, Monica, Rasmussen, Kasper Dindler, Much, Christian, Azzi, Chiara, Perlas, Emerald, Morgan, Marcos, O'Carroll, Dónal
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199480/