The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism
The formation of a laminar structure such as the mammalian neocortex relies on the coordinated migration of different subtypes of excitatory pyramidal neurons in specific layers. Cyclin-dependent kinase 5 (Cdk5) is a master regulator of pyramidal neuron migration. Recently, we have shown that Cdk5 b...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
The Company of Biologists
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199128/ |