Warped linear mixed models for the genetic analysis of transformed phenotypes
Linear mixed models (LMMs) are a powerful and established tool for studying genotype–phenotype relationships. A limitation of the LMM is that the model assumes Gaussian distributed residuals, a requirement that rarely holds in practice. Violations of this assumption can lead to false conclusions and...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Pub. Group
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199105/ |