Spatial regulation of tumor cell protrusions by RhoC

Systemic metastasis is the dissemination of cancer cells from the primary tumor to distant organs and is the primary cause of death in cancer patients. How do cancer cells leave the primary tumor mass? The ability of the tumor cells to form different types of actin-rich protrusions including invasiv...

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Bibliographic Details
Main Authors: Bravo-Cordero, Jose J, Hodgson, Louis, Condeelis, John S
Format: Online
Language:English
Published: Landes Bioscience 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198350/