Efficacy of Malarone® in Dogs Naturally Infected with Babesia gibsoni

The efficacy of Malarone® alone and in combination with doxycycline (DOXY) against Babesia gibsoni infections was examined in 8 dogs. In all dogs except one treated with Malarone®, parasitemia decreased, and anemia improved soon after initiation of treatment. However, 3 of 4 dogs treated with Malaro...

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Bibliographic Details
Main Authors: IGUCHI, Aiko, SHIRANAGA, Nobuyuki, MATSUU, Aya, HIKASA, Yoshiaki
Format: Online
Language:English
Published: The Japanese Society of Veterinary Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197161/
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Summary:The efficacy of Malarone® alone and in combination with doxycycline (DOXY) against Babesia gibsoni infections was examined in 8 dogs. In all dogs except one treated with Malarone®, parasitemia decreased, and anemia improved soon after initiation of treatment. However, 3 of 4 dogs treated with Malarone® relapsed, and relapse was inhibited in 2 of 4 dogs treated with Malarone® and DOXY. All relapsed dogs responded well to the second treatment, but 1 dog relapsed again and did not respond to the third treatment. Malarone® may be useful for acute stage of B. gibsoni infections, and at least second repeating treatment might be effective.