Integrated Control Of Hepatic Lipogenesis Vs. Glucose Production Requires FoxO Transcription Factors

Integrated Control Of Hepatic Lipogenesis Vs. Glucose Production Requires FoxO Transcription Factors

Insulin integrates hepatic glucose and lipid metabolism, directing nutrients to storage as glycogen and triglyceride. In type 2 diabetes, levels of the former are low and the latter are exaggerated, posing a pathophysiologic and therapeutic conundrum. A branching model of insulin signaling, with Fox...

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Bibliographic Details
Main Authors: Haeusler, Rebecca A., Hartil, Kirsten, Vaitheesvaran, Bhavapriya, Arrieta–Cruz, Isabel, Knight, Colette M., Cook, Joshua R., Kammoun, Helene L., Febbraio, Mark A., Gutierrez–Juarez, Roger, Kurland, Irwin J., Accili, Domenico
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197140/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197140/

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