Worm Proteins of Schistosoma mansoni Reduce the Severity of Experimental Chronic Colitis in Mice by Suppressing Colonic Proinflammatory Immune Responses

Although helminthic therapy as a possible new option to treat inflammatory bowel disease is a well-established concept by now, the search for immunomodulatory helminth-derived compounds and their mechanisms of action is still ongoing. We investigated the therapeutic potential and the underlying immu...

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Bibliographic Details
Main Authors: Heylen, Marthe, Ruyssers, Nathalie E., De Man, Joris G., Timmermans, Jean-Pierre, Pelckmans, Paul A., Moreels, Tom G., De Winter, Benedicte Y.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196959/