Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKCβ/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1

Up-regulated HMGB1 in EAM directly led to collagen deposition by a PKCβ/Erk1/2-dependent pathway: cardiac fibroblast/myofibroblast might be another source of HMGB1

High mobility group box 1 (HMGB1), an important inflammatory mediator, is actively secreted by immune cells and some non-immune cells or passively released by necrotic cells. HMGB1 has been implicated in many inflammatory diseases. Our previous published data demonstrated that HMGB1 was up-regulated...

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Bibliographic Details
Main Authors: Su, Zhaoliang, Yin, Jingping, Wang, Ting, Sun, Yingkun, Ni, Ping, Ma, Rui, Zhu, Haitao, Zheng, Dong, Shen, Huiling, Xu, Wenlin, Xu, Huaxi
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196650/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196650/

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