Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature

Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature

Chondroblastic osteosarcoma (COS), a subgroup of intramedullary osteosarcoma (OS), is the most common osteosarcoma that occurs in adolescents and early adulthood. The COS has similar clinical and radiological features to those of conventional OS. We present a case of 20-year-old male patient with th...

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Main Authors: Khandekar, Shubhangi, Dive, Alka, Munde, Prashant, Fande, Prajakta Zade
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196301/
id pubmed-4196301
recordtype oai_dc
spelling pubmed-41963012014-10-17 Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature Khandekar, Shubhangi Dive, Alka Munde, Prashant Fande, Prajakta Zade Case Report Chondroblastic osteosarcoma (COS), a subgroup of intramedullary osteosarcoma (OS), is the most common osteosarcoma that occurs in adolescents and early adulthood. The COS has similar clinical and radiological features to those of conventional OS. We present a case of 20-year-old male patient with the chief complaint of pain and swelling in the left zygomatic region. The computed tomography (CT) and three-dimensional (3D) CT face showed erosion, calcific foci, sunray type of spicules suggestive of OS. On fine-needle aspiration cytology (FNAC) examination, initial diagnosis was malignant chondroid lesion, with differential diagnosis of mesenchymal chrondrosarcoma, COS on incisional biopsy and finally COS on excisional biopsy. The patient underwent radical resection of left zygomatic arch, followed by chemotherapy. Although clinically unsuspected in this unusual site, histopathology along with immunohistochemistry (IHC) results confirmed the COS. Because zygomatic location of COS is very rare, this report aimed to discuss clinical, radiographic, histopathologic, IHC findings and diagnostic pitfalls of COS in light of the literature. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC4196301/ /pubmed/25328313 http://dx.doi.org/10.4103/0973-029X.140791 Text en Copyright: © Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Khandekar, Shubhangi
Dive, Alka
Munde, Prashant
Fande, Prajakta Zade
spellingShingle Khandekar, Shubhangi
Dive, Alka
Munde, Prashant
Fande, Prajakta Zade
Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature
author_facet Khandekar, Shubhangi
Dive, Alka
Munde, Prashant
Fande, Prajakta Zade
author_sort Khandekar, Shubhangi
title Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature
title_short Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature
title_full Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature
title_fullStr Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature
title_full_unstemmed Chondroblastic osteosarcoma of the left zygomatic bone: Rare case report and review of the literature
title_sort chondroblastic osteosarcoma of the left zygomatic bone: rare case report and review of the literature
description Chondroblastic osteosarcoma (COS), a subgroup of intramedullary osteosarcoma (OS), is the most common osteosarcoma that occurs in adolescents and early adulthood. The COS has similar clinical and radiological features to those of conventional OS. We present a case of 20-year-old male patient with the chief complaint of pain and swelling in the left zygomatic region. The computed tomography (CT) and three-dimensional (3D) CT face showed erosion, calcific foci, sunray type of spicules suggestive of OS. On fine-needle aspiration cytology (FNAC) examination, initial diagnosis was malignant chondroid lesion, with differential diagnosis of mesenchymal chrondrosarcoma, COS on incisional biopsy and finally COS on excisional biopsy. The patient underwent radical resection of left zygomatic arch, followed by chemotherapy. Although clinically unsuspected in this unusual site, histopathology along with immunohistochemistry (IHC) results confirmed the COS. Because zygomatic location of COS is very rare, this report aimed to discuss clinical, radiographic, histopathologic, IHC findings and diagnostic pitfalls of COS in light of the literature.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196301/
_version_ 1613144528751951872

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