MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin

Recent findings have revealed that dysregulated miRNAs contribute significantly to autophagy and chemoresistance. Pharmacologically targeting autophagy-related miRNAs is a novel strategy to reverse drug resistance. Here, we report a novel function of isoliquiritigenin (ISL) as a natural inhibitor of...

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Bibliographic Details
Main Authors: Wang, Zhiyu, Wang, Neng, Liu, Pengxi, Chen, Qianjun, Situ, Honglin, Xie, Ting, Zhang, Jianxing, Peng, Cheng, Lin, Yi, Chen, Jianping
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4196180/