Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele

Mapping early fate determination in Lgr5+ crypt stem cells using a novel Ki67-RFP allele

Cycling Lgr5+ stem cells fuel the rapid turnover of the adult intestinal epithelium. The existence of quiescent Lgr5+ cells has been reported, while an alternative quiescent stem cell population is believed to reside at crypt position +4. Here, we generated a novel Ki67RFP knock-in allele that ident...

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Bibliographic Details
Main Authors: Basak, Onur, van de Born, Maaike, Korving, Jeroen, Beumer, Joep, van der Elst, Stefan, van Es, Johan H, Clevers, Hans
Format: Online
Language:English
Published: BlackWell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195772/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195772/

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