Reducing Bias in Cancer Research: Application of Propensity Score Matching

In cancer observational studies, differences between groups on confounding variables may have a significant effect on results when examining health outcomes. This study demonstrates the utility of propensity score matching to balance a non-cancer and cancer cohort of older adults on multiple relevan...

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Main Authors: Reeve, Bryce B., Smith, Ashley Wilder, Arora, Neeraj K., Hays, Ron D.
Format: Online
Language:English
Published: CENTERS for MEDICARE & MEDICAID SERVICES 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195028/
id pubmed-4195028
recordtype oai_dc
spelling pubmed-41950282014-11-04 Reducing Bias in Cancer Research: Application of Propensity Score Matching Reeve, Bryce B. Smith, Ashley Wilder Arora, Neeraj K. Hays, Ron D. Quality of Life of Cancer Patients In cancer observational studies, differences between groups on confounding variables may have a significant effect on results when examining health outcomes. This study demonstrates the utility of propensity score matching to balance a non-cancer and cancer cohort of older adults on multiple relevant covariates. This approach matches cases to controls on a single indicator, the propensity score, rather than multiple variables. Results indicated that propensity score matching is an efficient and useful way to create a matched case-control study out of a large cohort study, and allows confidence in the strength of the observed outcomes of the study. CENTERS for MEDICARE & MEDICAID SERVICES 2008 /pmc/articles/PMC4195028/ /pubmed/18773615 Text en
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Reeve, Bryce B.
Smith, Ashley Wilder
Arora, Neeraj K.
Hays, Ron D.
spellingShingle Reeve, Bryce B.
Smith, Ashley Wilder
Arora, Neeraj K.
Hays, Ron D.
Reducing Bias in Cancer Research: Application of Propensity Score Matching
author_facet Reeve, Bryce B.
Smith, Ashley Wilder
Arora, Neeraj K.
Hays, Ron D.
author_sort Reeve, Bryce B.
title Reducing Bias in Cancer Research: Application of Propensity Score Matching
title_short Reducing Bias in Cancer Research: Application of Propensity Score Matching
title_full Reducing Bias in Cancer Research: Application of Propensity Score Matching
title_fullStr Reducing Bias in Cancer Research: Application of Propensity Score Matching
title_full_unstemmed Reducing Bias in Cancer Research: Application of Propensity Score Matching
title_sort reducing bias in cancer research: application of propensity score matching
description In cancer observational studies, differences between groups on confounding variables may have a significant effect on results when examining health outcomes. This study demonstrates the utility of propensity score matching to balance a non-cancer and cancer cohort of older adults on multiple relevant covariates. This approach matches cases to controls on a single indicator, the propensity score, rather than multiple variables. Results indicated that propensity score matching is an efficient and useful way to create a matched case-control study out of a large cohort study, and allows confidence in the strength of the observed outcomes of the study.
publisher CENTERS for MEDICARE & MEDICAID SERVICES
publishDate 2008
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195028/
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