Radioiodine Therapy in Differentiated Thyroid Cancer: The First Targeted Therapy in Oncology
Iodide uptake across the membranes of thyroid follicular cells and cancer cells occurs through an active transport process mediated by the sodium-iodide symporter (NIS). The rat and human NIS-coding genes were cloned and identified in 1996. Evaluation of NIS gene and protein expression is critical f...
| Main Authors: | , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
Korean Endocrine Society
2014
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192819/ |