Pou3f4-Mediated Regulation of Ephrin-B2 Controls Temporal Bone Development in the Mouse

The temporal bone encases conductive and sensorineural elements of the ear. Mutations of POU3F4 are associated with unique temporal bone abnormalities and X-linked mixed deafness (DFNX2/DFN3). However, the target genes and developmental processes controlled by POU3F4 transcription factor activity ha...

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Bibliographic Details
Main Authors: Raft, Steven, Coate, Thomas M., Kelley, Matthew W., Crenshaw, E. Bryan, Wu, Doris K.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192298/