What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems
Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate selection in viral infection, cell-cycle control and d...
Main Authors: | , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Oxford University Press
2014
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191413/ |