Reaching a consensus on the mechanism of dynamin?
Among the proteins involved in lipid membrane remodeling in intracellular traffic, dynamin has been the focus of many studies, as it was the first protein shown to be mechanistically involved in membrane fission: the reaction by which a vesicle neck can be severed to release a free vesicle. After al...
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| Format: | Online |
| Language: | English |
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Faculty of 1000 Ltd
2014
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191246/ |
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pubmed-41912462014-11-05 Reaching a consensus on the mechanism of dynamin? Roux, Aurélien Review Article Among the proteins involved in lipid membrane remodeling in intracellular traffic, dynamin has been the focus of many studies, as it was the first protein shown to be mechanistically involved in membrane fission: the reaction by which a vesicle neck can be severed to release a free vesicle. After almost 25 years of research, a wide variety of data from various techniques has been acquired on the mechanism by which dynamin breaks membranes. However, the literature may sometimes sound confusing, and the primary goal of this review will be to provide a stepping stone towards a potential consensus on how dynamin may work. I will then discuss the most recent findings in light of previous work, and the future possible lines of research in the field of dynamin. Faculty of 1000 Ltd 2014-10-01 /pmc/articles/PMC4191246/ /pubmed/25374664 http://dx.doi.org/10.12703/P6-86 Text en © 2014 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode All F1000Prime Reports articles are distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Roux, Aurélien |
| spellingShingle |
Roux, Aurélien Reaching a consensus on the mechanism of dynamin? |
| author_facet |
Roux, Aurélien |
| author_sort |
Roux, Aurélien |
| title |
Reaching a consensus on the mechanism of dynamin? |
| title_short |
Reaching a consensus on the mechanism of dynamin? |
| title_full |
Reaching a consensus on the mechanism of dynamin? |
| title_fullStr |
Reaching a consensus on the mechanism of dynamin? |
| title_full_unstemmed |
Reaching a consensus on the mechanism of dynamin? |
| title_sort |
reaching a consensus on the mechanism of dynamin? |
| description |
Among the proteins involved in lipid membrane remodeling in intracellular traffic, dynamin has been the focus of many studies, as it was the first protein shown to be mechanistically involved in membrane fission: the reaction by which a vesicle neck can be severed to release a free vesicle. After almost 25 years of research, a wide variety of data from various techniques has been acquired on the mechanism by which dynamin breaks membranes. However, the literature may sometimes sound confusing, and the primary goal of this review will be to provide a stepping stone towards a potential consensus on how dynamin may work. I will then discuss the most recent findings in light of previous work, and the future possible lines of research in the field of dynamin. |
| publisher |
Faculty of 1000 Ltd |
| publishDate |
2014 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191246/ |
| _version_ |
1613142516760051712 |