Serum cholesterol selectively regulates glucocorticoid sensitivity through activation of JNK
Glucocorticoids (Gc) are potent anti-inflammatory agents with wide clinical application. We have previously shown that increased serum concentration significantly attenuates regulation of a simple Gc-responsive reporter. We now find that glucocorticoid receptor (GR) regulation of some endogenous tra...
Main Authors: | , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Bioscientifica Ltd
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191185/ |