TRIM28 regulates RNA polymerase II promoter proximal pausing and pause release

TRIM28 regulates RNA polymerase II promoter proximal pausing and pause release

Promoter proximal pausing of RNA polymerase II (Pol II) is a major checkpoint in transcription. An unbiased search for novel human proteins that could regulate paused Pol II at the HSPA1B gene identified TRIM28. In vitro analyses indicated HSF1-dependent attenuation of Pol II pausing upon TRIM28 dep...

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Bibliographic Details
Main Authors: Bunch, Heeyoun, Zheng, Xiaofeng, Burkholder, Adam, Dillon, Simon T., Motola, Shmulik, Birrane, Gabriel, Ebmeier, Christopher C., Levine, Stuart, Fargo, David, Hu, Guang, Taatjes, Dylan J., Calderwood, Stuart K.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189995/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189995/

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