Hypomethylation of the promoter of the catalytic subunit of protein phosphatase 2A in response to hyperglycemia

In order to identify epigenetic mechanisms through which hyperglycemia can affect gene expression durably in β cells, we screened DNA methylation changes induced by high glucose concentrations (25 mmol/L) in the BTC3 murine cell line, using an epigenome‐wide approach. Exposure of BTC3 cells to high...

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Bibliographic Details
Main Authors: Tros, Fabiola, Meirhaeghe, Aline, Hadjadj, Samy, Amouyel, Philippe, Bougnères, Pierre, Fradin, Delphine
Format: Online
Language:English
Published: Wiley Periodicals, Inc. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187575/