Reduced inhibitory gate in the barrel cortex of Neuroligin3R451C knock‐in mice, an animal model of autism spectrum disorders

Neuroligins are postsynaptic adhesion molecules that interacting with presynaptic neurexins ensure the cross‐talk between pre‐ and postsynaptic specializations. Rare mutations in neurexin–neuroligin genes have been linked to autism spectrum disorders (ASDs). One of these, the R451C mutation of the g...

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Bibliographic Details
Main Authors: Cellot, Giada, Cherubini, Enrico
Format: Online
Language:English
Published: Wiley Periodicals, Inc. 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4187543/