A CpG island methylator phenotype of colorectal cancer that is contiguous with conventional adenomas, but not serrated polyps
A subset of colorectal cancers (CRCs) harbor the CpG island methylator phenotype (CIMP), with concurrent multiple promoter hypermethylation of tumor-related genes. A serrated pathway in which CIMP is developed from serrated polyps is proposed. The present study characterized CIMP and morphologically...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
D.A. Spandidos
2014
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186580/ |