Regulation of prostaglandin EP1 and EP4 receptor signaling by carrier-mediated ligand reuptake

After synthesis and release from cells, prostaglandin E2 (PGE2) undergoes reuptake by the prostaglandin transporter (PGT), followed by cytoplasmic oxidation. Although genetic inactivation of PGT in mice and humans results in distinctive phenotypes, and although experiments in localized environments...

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Bibliographic Details
Main Authors: Chi, Yuling, Suadicani, Sylvia O, Schuster, Victor L
Format: Online
Language:English
Published: Blackwell Publishing Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186417/