PSMA-Specific CAR-Engineered T Cells Eradicate Disseminated Prostate Cancer in Preclinical Models

Immunology-based interventions have been proposed as a promising curative chance to effectively attack postoperative minimal residual disease and distant metastatic localizations of prostate tumors. We developed a chimeric antigen receptor (CAR) construct targeting the human prostate-specific membra...

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Bibliographic Details
Main Authors: Zuccolotto, Gaia, Fracasso, Giulio, Merlo, Anna, Montagner, Isabella Monia, Rondina, Maria, Bobisse, Sara, Figini, Mariangela, Cingarlini, Sara, Colombatti, Marco, Zanovello, Paola, Rosato, Antonio
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184866/