Clathrin Assembly Protein CALM Plays a Critical Role in KIT Signaling by Regulating Its Cellular Transport from Early to Late Endosomes in Hematopoietic Cells

CALM is implicated in the formation of clathrin-coated vesicles, which mediate endocytosis and intracellular trafficking of growth factor receptors and nutrients. We previously found that CALM-deficient mice suffer from severe anemia due to the impaired clathrin-mediated endocytosis of transferrin r...

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Bibliographic Details
Main Authors: Rai, Shinya, Tanaka, Hirokazu, Suzuki, Mai, Ogoh, Honami, Taniguchi, Yasuhiro, Morita, Yasuyoshi, Shimada, Takahiro, Tanimura, Akira, Matsui, Keiko, Yokota, Takafumi, Oritani, Kenji, Tanabe, Kenji, Watanabe, Toshio, Kanakura, Yuzuru, Matsumura, Itaru
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184852/