HIV Acquisition Is Associated with Increased Antimicrobial Peptides and Reduced HIV Neutralizing IgA in the Foreskin Prepuce of Uncircumcised Men

Randomized trials of male circumcision (MC) for HIV prevention have shown that the foreskin is a major site of HIV acquisition among heterosexual men, but a number of barriers to MC programs mean that many HIV-susceptible men remain uncircumcised. The immune correlates of HIV acquisition in the fore...

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Bibliographic Details
Main Authors: Hirbod, Taha, Kong, Xiangrong, Kigozi, Godgrey, Ndyanabo, Anthony, Serwadda, David, Prodger, Jessica L., Tobian, Aaron A., Nalugoda, Fred, Wawer, Maria J., Shahabi, Kamnoosh, Rojas, Olga L., Gommerman, Jennifer L., Broliden, Kristina, Kaul, Rupert, Gray, Ronald H.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183701/