Analysis of Candida albicans Mutants Defective in the Cdk8 Module of Mediator Reveal Links between Metabolism and Biofilm Formation

Analysis of Candida albicans Mutants Defective in the Cdk8 Module of Mediator Reveal Links between Metabolism and Biofilm Formation

Candida albicans biofilm formation is a key virulence trait that involves hyphal growth and adhesin expression. Pyocyanin (PYO), a phenazine secreted by Pseudomonas aeruginosa, inhibits both C. albicans biofilm formation and development of wrinkled colonies. Using a genetic screen, we identified tw...

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Bibliographic Details
Main Authors: Lindsay, Allia K., Morales, Diana K., Liu, Zhongle, Grahl, Nora, Zhang, Anda, Willger, Sven D., Myers, Lawrence C., Hogan, Deborah A.
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183431/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183431/

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