Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements

Inter-individual variation in gene regulatory elements is hypothesized to play a causative role in adverse drug reactions and reduced drug activity. However, relatively little is known about the location and function of drug-dependent elements. To uncover drug-associated elements in a genome-wide ma...

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Bibliographic Details
Main Authors: Smith, Robin P., Eckalbar, Walter L., Morrissey, Kari M., Luizon, Marcelo R., Hoffmann, Thomas J., Sun, Xuefeng, Jones, Stacy L., Force Aldred, Shelley, Ramamoorthy, Anuradha, Desta, Zeruesenay, Liu, Yunlong, Skaar, Todd C., Trinklein, Nathan D., Giacomini, Kathleen M., Ahituv, Nadav
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183418/