Trans-ethnic genome-wide association study of colorectal cancer identifies a new susceptibility locus in VTI1A

The genetic basis of sporadic colorectal cancer (CRC) is not well explained by known risk polymorphisms. Here we perform a meta-analysis of two genome-wide association studies in 2,627 cases and 3,797 controls of Japanese ancestry and 1,894 cases and 4,703 controls of African ancestry, to identify g...

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Main Authors: Wang, Hansong, Burnett, Terrilea, Kono, Suminori, Haiman, Christopher A., Iwasaki, Motoki, Wilkens, Lynne R., Loo, Lenora W.M., Berg, David Van Den, Kolonel, Laurence N., Henderson, Brian E., Keku, Temitope O., Sandler, Robert S., Signorello, Lisa B., Blot, William J., Newcomb, Polly A., Pande, Mala, Amos, Christopher I., West, Dee W., Bézieau, Stéphane, Berndt, Sonja I., Zanke, Brent W., Hsu, Li, Lindor, Noralane M., Haile, Robert W., Hopper, John L., Jenkins, Mark A., Gallinger, Steven, Casey, Graham, Stenzel, Stephanie L., Schumacher, Fredrick R., Peters, Ulrike, Gruber, Stephen B., Tsugane, Shoichiro, Stram, Daniel O., Marchand, Loïc Le
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180879/