A critical role for mTORC1 in erythropoiesis and anemia

Red blood cells (RBC) must coordinate their rate of growth and proliferation with the availability of nutrients, such as iron, but the signaling mechanisms that link the nutritional state to RBC growth are incompletely understood. We performed a screen for cell types that have high levels of signali...

Full description

Bibliographic Details
Main Authors: Knight, Zachary A, Schmidt, Sarah F, Birsoy, Kivanc, Tan, Keith, Friedman, Jeffrey M
Format: Online
Language:English
Published: eLife Sciences Publications, Ltd 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179304/