Uremic Toxins Enhance Statin-Induced Cytotoxicity in Differentiated Human Rhabdomyosarcoma Cells

The risk of myopathy and rhabdomyolysis is considerably increased in statin users with end-stage renal failure (ESRF). Uremic toxins, which accumulate in patients with ESRF, exert cytotoxic effects that are mediated by various mechanisms. Therefore, accumulation of uremic toxins might increase stati...

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Bibliographic Details
Main Authors: Uchiyama, Hitoshi, Tsujimoto, Masayuki, Shinmoto, Tadakazu, Ogino, Hitomi, Oda, Tomoko, Yoshida, Takuya, Furukubo, Taku, Izumi, Satoshi, Yamakawa, Tomoyuki, Tachiki, Hidehisa, Minegaki, Tetsuya, Nishiguchi, Kohshi
Format: Online
Language:English
Published: MDPI 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179151/