Carboxypeptidase E Is a Novel Modulator of RANKL-Induced Osteoclast Differentiation

Osteoclasts are large polykaryons that have the unique capacity to degrade bone and are generated by the differentiation of myeloid lineage progenitors. To identify the genes involved in osteoclast development, we performed microarray analysis, and we found that carboxypeptidase E (CPE), a prohormon...

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Bibliographic Details
Main Authors: Kim, Hyun-Ju, Hong, JungMin, Yoon, Hye-Jin, Yoon, Young-Ran, Kim, Shin-Yoon
Format: Online
Language:English
Published: Korean Society for Molecular and Cellular Biology 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179137/