Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II

Mastl is required for timely activation of APC/C in meiosis I and Cdk1 reactivation in meiosis II

The Greatwall kinase orthologue Mastl regulates timely activation of APC/C to allow meiosis I exit and suppresses PP2A activity and thereby allows the rapid rise of Cdk1 activity that is necessary for meiosis II entry in mouse oocytes.

Bibliographic Details
Main Authors: Adhikari, Deepak, Diril, M. Kasim, Busayavalasa, Kiran, Risal, Sanjiv, Nakagawa, Shoma, Lindkvist, Rebecca, Shen, Yan, Coppola, Vincenzo, Tessarollo, Lino, Kudo, Nobuaki R., Kaldis, Philipp, Liu, Kui
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178961/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178961/

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