Flavonoid Fraction of Bergamot Juice Reduces LPS-Induced Inflammatory Response through SIRT1-Mediated NF-κB Inhibition in THP-1 Monocytes

Plant polyphenols exert anti-inflammatory activity through both anti-oxidant effects and modulation of pivotal pro-inflammatory genes. Recently, Citrus bergamia has been studied as a natural source of bioactive molecules with antioxidant activity, but few studies have focused on molecular mechanisms...

Full description

Bibliographic Details
Main Authors: Risitano, Roberto, Currò, Monica, Cirmi, Santa, Ferlazzo, Nadia, Campiglia, Pietro, Caccamo, Daniela, Ientile, Riccardo, Navarra, Michele
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178028/