A Possible Non-genomic Epileptogenic Properties of Estradiol Attenuated by MK801 and DNQX in Amygdala Kindled Rats

Although the epileptogenic properties of estrogens have been widely demonstrated in several models and species, the mechanism(s) by which estrogens can acutely change seizure parameters including after discharge and seizure durationremains to be determined. In the present study, we examined the role...

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Main Authors: Saberi, Mehdi, Saberi, Fatemeh, Vesali Mahmoud, Roshanak
Format: Online
Language:English
Published: Shaheed Beheshti University of Medical Sciences 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177660/
id pubmed-4177660
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spelling pubmed-41776602014-09-30 A Possible Non-genomic Epileptogenic Properties of Estradiol Attenuated by MK801 and DNQX in Amygdala Kindled Rats Saberi, Mehdi Saberi, Fatemeh Vesali Mahmoud, Roshanak Original Article Although the epileptogenic properties of estrogens have been widely demonstrated in several models and species, the mechanism(s) by which estrogens can acutely change seizure parameters including after discharge and seizure durationremains to be determined. In the present study, we examined the role of NMDA (N-methyl-D-aspartate), non-NMDA andestrogen receptors in estradiol benzoate(EB) effects on kindled seizure parameters. Shaheed Beheshti University of Medical Sciences 2014 /pmc/articles/PMC4177660/ /pubmed/25276200 Text en © 2014 by School of Pharmacy, Shaheed Beheshti University of Medical Sciences and Health Services This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Saberi, Mehdi
Saberi, Fatemeh
Vesali Mahmoud, Roshanak
spellingShingle Saberi, Mehdi
Saberi, Fatemeh
Vesali Mahmoud, Roshanak
A Possible Non-genomic Epileptogenic Properties of Estradiol Attenuated by MK801 and DNQX in Amygdala Kindled Rats
author_facet Saberi, Mehdi
Saberi, Fatemeh
Vesali Mahmoud, Roshanak
author_sort Saberi, Mehdi
title A Possible Non-genomic Epileptogenic Properties of Estradiol Attenuated by MK801 and DNQX in Amygdala Kindled Rats
title_short A Possible Non-genomic Epileptogenic Properties of Estradiol Attenuated by MK801 and DNQX in Amygdala Kindled Rats
title_full A Possible Non-genomic Epileptogenic Properties of Estradiol Attenuated by MK801 and DNQX in Amygdala Kindled Rats
title_fullStr A Possible Non-genomic Epileptogenic Properties of Estradiol Attenuated by MK801 and DNQX in Amygdala Kindled Rats
title_full_unstemmed A Possible Non-genomic Epileptogenic Properties of Estradiol Attenuated by MK801 and DNQX in Amygdala Kindled Rats
title_sort possible non-genomic epileptogenic properties of estradiol attenuated by mk801 and dnqx in amygdala kindled rats
description Although the epileptogenic properties of estrogens have been widely demonstrated in several models and species, the mechanism(s) by which estrogens can acutely change seizure parameters including after discharge and seizure durationremains to be determined. In the present study, we examined the role of NMDA (N-methyl-D-aspartate), non-NMDA andestrogen receptors in estradiol benzoate(EB) effects on kindled seizure parameters.
publisher Shaheed Beheshti University of Medical Sciences
publishDate 2014
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177660/
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