A Rapid and Sensitive HPLC-Fluorescence Method for Determination of Mirtazapine and Its two Major Metabolites in Human Plasma

A rapid and sensitive HPLC method has been developed for the quantification of mirtazapine (MRZ), a noradrenergic and specific serotonergic inhibitor antidepressant (NaSSA) and its two major metabolites N-desmethyl mirtazapine (NDM) and 8-hydroxymirtazapine (8-OHM) in human plasma.

Bibliographic Details
Main Authors: Lavasani, Hoda, Giorgi, Mario, Sheikholeslami, Behjat, Hedayati, Mohammadhasan, Rouini, Mohammad Reza
Format: Online
Language:English
Published: Shaheed Beheshti University of Medical Sciences 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177645/