Docetaxel Loaded PEG-PLGA Nanoparticles: Optimized Drug Loading, In-vitro Cytotoxicity and In-vivo Antitumor Effect

Docetaxel Loaded PEG-PLGA Nanoparticles: Optimized Drug Loading, In-vitro Cytotoxicity and In-vivo Antitumor Effect

In this study a 3-factor, 3-level Box-Behnken design was used to prepare optimized docetaxel (DTX) loaded pegylated poly lactide-co-glycolide (PEG-PLGA) Nanoparticles (NPs) with polymer concentration (X1), drug concentration (X2) and ratio of the organic to aqueous solvent (X3) as the independent va...

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Bibliographic Details
Main Authors: Noori Koopaei, Mona, Khoshayand, Mohammad Reza, Mostafavi, Seyed Hossein, Amini, Mohsen, Khorramizadeh, Mohammad Reza, Jeddi Tehrani, Mahmood, Atyabi, Fatemeh, Dinarvand, Rassoul
Format: Online
Language:English
Published: Shaheed Beheshti University of Medical Sciences 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177642/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177642/

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