Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization

Zinc finger oxidation of Fpg/Nei DNA glycosylases by 2-thioxanthine: biochemical and X-ray structural characterization

DNA glycosylases from the Fpg/Nei structural superfamily are base excision repair enzymes involved in the removal of a wide variety of mutagen and potentially lethal oxidized purines and pyrimidines. Although involved in genome stability, the recent discovery of synthetic lethal relationships betwee...

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Bibliographic Details
Main Authors: Biela, Artur, Coste, Franck, Culard, Françoise, Guerin, Martine, Goffinont, Stéphane, Gasteiger, Karola, Cieśla, Jarosław, Winczura, Alicja, Kazimierczuk, Zygmunt, Gasparutto, Didier, Carell, Thomas, Tudek, Barbara, Castaing, Bertrand
Format: Online
Language:English
Published: Oxford University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176347/

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