The Notch Ligand Jagged1 as a Target for Anti-Tumor Therapy
The Notch pathway is increasingly attracting attention as a source of therapeutic targets for cancer. Ligand-induced Notch signaling has been implicated in various aspects of cancer biology; as a consequence, pan-Notch inhibitors and therapeutic antibodies targeting one or more of the Notch receptor...
Main Authors: | , , , |
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Format: | Online |
Language: | English |
Published: |
Frontiers Media S.A.
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174884/ |