Co-delivery of Doxorubicin and Bmi1 siRNA by Folate Receptor Targeted Liposomes Exhibits Enhanced Anti-Tumor Effects in vitro and in vivo

Co-delivery of Doxorubicin and Bmi1 siRNA by Folate Receptor Targeted Liposomes Exhibits Enhanced Anti-Tumor Effects in vitro and in vivo

Bmi1 gene overexpression is found in various human tumors and has been shown as a potential target for gene treatment. However, siRNA-based treatments targeting Bmi1 gene have been restricted to limited delivery, low bioavailability and hence relatively reduced efficacy. To overcome these barriers,...

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Bibliographic Details
Main Authors: Yang, Tan, Li, Bin, Qi, Shibo, Liu, Yong, Gai, Yongkang, Ye, Peng, Yang, Guang, Zhang, Wendian, Zhang, Peng, He, Xingxing, Li, Weijie, Zhang, Zhiping, Xiang, Guangya, Xu, Chuanrui
Format: Online
Language:English
Published: Ivyspring International Publisher 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173760/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173760/

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