Development of prediction tools for diarrhea and rash in breast cancer patients receiving lapatinib in combination with capecitabine

Lapatinib and capecitabine (L-CAP) is effective in HER-2 positive patients with metastatic breast cancer (MBC). However, moderate to severe diarrhea and rash (≥ grade 2) are problematic dose limiting toxicities. Since risk may vary over the course of therapy, we developed repeated measures models to...

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Bibliographic Details
Main Authors: Dranitsaris, George, Lacouture, Mario E.
Format: Online
Language:English
Published: Springer US 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173070/