The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment

The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment

Kovács et al. examine the role of the Src family kinases Hck, Fgr, and Lyn in immune cell–mediated inflammation. Using arthritis and skin inflammation models, the authors show that mice lacking hematopoietic Hck, Fgr, and Lyn are protected from these inflammatory diseases, showing loss of myeloid ce...

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Bibliographic Details
Main Authors: Kovács, Miklós, Németh, Tamás, Jakus, Zoltán, Sitaru, Cassian, Simon, Edina, Futosi, Krisztina, Botz, Bálint, Helyes, Zsuzsanna, Lowell, Clifford A., Mócsai, Attila
Format: Online
Language:English
Published: The Rockefeller University Press 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172222/

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