Caspase-2 regulates oncogene-induced senescence
Cellular senescence is activated by numerous cellular insults, in particular those driving cancer formation, resulting in stable proliferation arrest and acquisition of specific features. By self-opposing to oncogenic stimulation, senescence is considered as a failsafe program, allowing, when functi...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Impact Journals LLC
2014
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170627/ |