Development of replication-competent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter

Survivin is a member of the inhibitors of apoptosis protein family. Here, we examined survivin expression and confirmed abundant survivin expression in bladder cancer cells. This expression pattern indicated that the transcriptional regulatory elements that control survivin expression could be utili...

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Bibliographic Details
Main Authors: Seo, Ho Kyung, Seo, Jeong Bin, Nam, Jae-Kook, Jeong, Kyung-Chae, Shin, Seung-Pil, Kim, In-Hoo, Lee, Sang Don, Lee, Sang-Jin
Format: Online
Language:English
Published: Impact Journals LLC 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170600/