Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis

Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis

Di-(2-ethylhexyl)-phthalate (DEHP) is a ubiquitously used endocrine disruptor.There is widespread exposure to DEHP in the general population which has raised substantial public concern due to its potential detrimental health effects. It is particularly pertinent to investigate the molecular mechanis...

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Bibliographic Details
Main Authors: Li, Xiaolin, Fang, Evandro Fei, Scheibye-Knudsen, Morten, Cui, Honghua, Qiu, Lu, Li, Jian, He, Yuping, Huang, Jing, Bohr, Vilhelm A., Ng, Tzi Bun, Guo, Hongwei
Format: Online
Language:English
Published: Nature Publishing Group 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170195/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170195/

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