Chemically Defined and Small Molecule-Based Generation of Human Cardiomyocytes

Existing methodologies for human induced pluripotent stem cell (hiPSC) cardiac differentiation are efficient but require the use of complex, undefined medium constituents that hinder further elucidation of the molecular mechanisms of cardiomyogenesis. Using hiPSCs derived under chemically defined co...

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Bibliographic Details
Main Authors: Burridge, Paul W., Matsa, Elena, Shukla, Praveen, Lin, Ziliang C., Churko, Jared M., Ebert, Antje D., Lan, Feng, Diecke, Sebastian, Huber, Bruno, Mordwinkin, Nicholas M., Plews, Jordan R., Abilez, Oscar J., Cui, Bianxiao, Gold, Joseph D., Wu, Joseph C.
Format: Online
Language:English
Published: 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169698/