Dimethyl Sulfoxide Damages Mitochondrial Integrity and Membrane Potential in Cultured Astrocytes

Dimethyl sulfoxide (DMSO) is a polar organic solvent that is used to dissolve neuroprotective or neurotoxic agents in neuroscience research. However, DMSO itself also has pharmacological and pathological effects on the nervous system. Astrocytes play a central role in maintaining brain homeostasis,...

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Bibliographic Details
Main Authors: Yuan, Chan, Gao, Junying, Guo, Jichao, Bai, Lei, Marshall, Charles, Cai, Zhiyou, Wang, Linmei, Xiao, Ming
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169574/