The Association of the Vanin-1 N131S Variant with Blood Pressure Is Mediated by Endoplasmic Reticulum-Associated Degradation and Loss of Function

The Association of the Vanin-1 N131S Variant with Blood Pressure Is Mediated by Endoplasmic Reticulum-Associated Degradation and Loss of Function

High blood pressure (BP) is the most common cardiovascular risk factor worldwide and a major contributor to heart disease and stroke. We previously discovered a BP-associated missense SNP (single nucleotide polymorphism)–rs2272996–in the gene encoding vanin-1, a glycosylphosphatidylinositol (GPI)-an...

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Bibliographic Details
Main Authors: Wang, Ya-Juan, Tayo, Bamidele O., Bandyopadhyay, Anupam, Wang, Heming, Feng, Tao, Franceschini, Nora, Tang, Hua, Gao, Jianmin, Sung, Yun Ju, Elston, Robert C., Williams, Scott M., Cooper, Richard S., Mu, Ting-Wei, Zhu, Xiaofeng
Format: Online
Language:English
Published: Public Library of Science 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169380/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169380/

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