Methylome, transcriptome, and PPARγ cistrome analyses reveal two epigenetic transitions in fat cells

Although DNA modification is adaptive to extrinsic demands, little is known about epigenetic alterations associated with adipose differentiation and reprogramming. We systematically characterized the global trends of our methylome and transcriptome data with reported PPARγ cistrome data. Our analysi...

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Bibliographic Details
Main Authors: Takada, Hitomi, Saito, Yutaka, Mituyama, Toutai, Wei, Zong, Yoshihara, Eiji, Jacinto, Sandra, Downes, Michael, Evans, Ronald M, Kida, Yasuyuki S
Format: Online
Language:English
Published: Landes Bioscience 2014
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169011/